outcome of paraquat poisoned patients treated with a commonly used therapeutic flowchart: a case series

نویسندگان

devanur rajashekhara murthy mahadeshwara prasad department of forensic medicine and toxicology, district hospital and chamarajanagar institute of medical sciences, chamarajanagar, karnataka, india

abhilash chennabasappa shimoga institute of medical science, shimoga, karnataka, india

چکیده

background: paraquat poisoning is a medical emergency challenge due to its inherent severe toxicity and unavailability of specific antidote for it. in this paper, a series of patients who were treated according to a commonly used treatment flowchart are presented. methods: this prospective observational study was carried out on paraquat poisoned patients admitted to district hospital, chamarajanagar and shimoga institute of medical sciences, shimoga, karnataka, india, during january 2013 to december 2014. results: six patients (4 women and 2 men) with median age of 23 [min-max: 18-42] years were studied. the majority of patients had respiratory distress (with an average spo2 of 60%), i.e. 4 out of 6 cases manifested with respiratory distress associated with dryness and burning sensation in mouth, throat and chest. oxygen therapy with mask in one case and by ventilator in rest of cases was required. except one patient who died on the first day and no further measurement of serum creatinine could be taken from her, all other patients developed increased creatinine. five out of 6 patients died mainly due to pulmonary sequels. in the only survived patient, gastrointestinal symptoms were predominant followed by acute renal failure and pulmonary congestion which were reverted with medical care indicated in the therapeutic flowchart. in post-mortem investigations, inflammatory infiltration in lungs was noted in all cases and acute tubular necrosis was seen in 3 cases. conclusion: renal insufficiency and pulmonary damage following severe paraquat poisoning are indicators of poor prognosis and may not be reversible with commonly used treatment approaches.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Outcome of Paraquat Poisoned Patients Treated with a Commonly Used Therapeutic Flowchart: A Case Series

Background: Paraquat poisoning is a medical emergency challenge due to its inherent severe toxicity and unavailability of specific antidote for it. In this paper, a series of patients who were treated according to a commonly used treatment flowchart are presented. Methods: This prospective observational study was carried out on paraquat poisoned patients admitted to District Hospital, Chamaraj...

متن کامل

Monocular Elevation Deficiency: A Case Series of Surgical Outcome

Background: Inferior rectus recession, Knapp procedure, partial tendon transposition, and combined procedure are different surgical procedures in the management of monocular elevation deficiency (MED). Only a few studies have been published on the management of this problem. In this study, we report our experience with patients with MED focusing on the indications and types of surgery in the so...

متن کامل

Outcome of Patients with Cholinergic Insecticide Poisoning Treated with Gastric Lavage: A Prospective Observational Cohort Study

Background: Gastric lavage (GL) is one of the most commonly used decontamination method for cholinergic insecticide ingestion in developing countries despite lack of supporting evidence. This study was designed to evaluate the outcome of patients with cholinergic insecticide poisoning treated with GL in regards to timing and frequency of the procedure. Methods: In this prospective observational...

متن کامل

a comparison of linguistic and pragmatic knowledge: a case of iranian learners of english

در این تحقیق دانش زبانشناسی و کاربردشناسی زبان آموزان ایرانی در سطح بالای متوسط مقایسه شد. 50 دانش آموز با سابقه آموزشی مشابه از شش آموزشگاه زبان مختلف در دو آزمون دانش زبانشناسی و آزمون دانش گفتار شناسی زبان انگلیسی شرکت کردند که سوالات هر دو تست توسط محقق تهیه شده بود. همچنین در این تحقیق کارایی کتابهای آموزشی زبان در فراهم آوردن درون داد کافی برای زبان آموزان ایرانی به عنوان هدف جانبی تحقیق ...

15 صفحه اول

Clearance Rate and BP-ANN Model in Paraquat Poisoned Patients Treated with Hemoperfusion

In order to investigate the effect of hemoperfusion (HP) on the clearance rate of paraquat (PQ) and develop a clearance model, 41 PQ-poisoned patients who acquired acute PQ intoxication received HP treatment. PQ concentrations were determined by high performance liquid chromatography (HPLC). According to initial PQ concentration, study subjects were divided into two groups: Low-PQ group (0.05-1...

متن کامل

Neurologic manifestations in patients with COVID-19: A case series

Background: There are very few reports about the neurological complications of COVID-19. Case Presentation: Herein we present neurological manifestations in 2 hospitalized patients with COVID-19. The patients showed most common symptoms of COVID-19 along with common conflicts in CT scans of lung such as ground-glass opacities (GGOs). First case revealed two episodes of generalized tonic–clonic...

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید


عنوان ژورنال:
asia pacific journal of medical toxicology

جلد ۴، شماره ۴، صفحات ۱۳۹-۱۴۲

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023